CD56+ monocytes have a dysregulated cytokine response to lipopolysaccharide and accumulate in rheumatoid arthritis and immunosenescence

@inproceedings{Krasselt2013CD56MH,
  title={CD56+ monocytes have a dysregulated cytokine response to lipopolysaccharide and accumulate in rheumatoid arthritis and immunosenescence},
  author={Marco Krasselt and Christoph G. O. Baerwald and Ulf Wagner and Manuela Rossol},
  booktitle={Arthritis research & therapy},
  year={2013}
}
INTRODUCTION Peripheral blood monocytes are no longer regarded as a homogeneous cell population, but can be differentiated both phenotypically and functionally into various subpopulations. In rheumatoid arthritis, the subpopulation of CD14bright/CD16+ monocyte is expanded and prone towards generation of Th17 cells. CD56+ monocytes represent a different subpopulation, which is also expanded in conditions associated with autoimmunity like inflammatory bowel diseases. The aim of the study was the… CONTINUE READING
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