CD55 is over-expressed in the tumour environment

  title={CD55 is over-expressed in the tumour environment},
  author={Lingna Li and Ian Spendlove and Jeffrey T Morgan and Lindy Durrant},
  journal={British Journal of Cancer},
  pages={80 - 86}
CD55 is a protein that protects cells from complement-mediated attack. 791Tgp72 is an antigen which has been used succesfully as a target for both tumour imaging and cancer vaccines. 791Tgp72 has recently been identified as CD55. Quantitative expression of CD55 in the tumour environment was therefore studied. Tumour cells showed a 4–100-fold increase in CD55 cell surface expression when compared to normal cells. Immunohistochemical staining of colorectal tumours also revealed high expression of… CONTINUE READING
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