CD45RO: a marker for BCR-mediated selection.

  title={CD45RO: a marker for BCR-mediated selection.},
  author={Stephen M. Jackson and Natessa Harp and Darshna Patel and Mark G. Henderson and Nicole Marie Roy and Marcie A Courtney and Andy D. Johnson and J. Donald Capra},
  journal={Scandinavian journal of immunology},
  volume={66 2-3},
We previously showed that IgH sequence alone minimally influenced germinal centre (GC) B-cell survival fate. As end-stage effector B cells are typically more mutated than founder GC B cells, we worked to develop an assay that would enrich for populations of GC B cells with progressively increasing numbers of somatic mutations, which could potentially be… CONTINUE READING