CD45-positive cells of the retina and their responsiveness to in vivo and in vitro treatment with IFN-gamma or anti-CD40.

@article{Gregerson2003CD45positiveCO,
  title={CD45-positive cells of the retina and their responsiveness to in vivo and in vitro treatment with IFN-gamma or anti-CD40.},
  author={Dale S Gregerson and Jing Yang},
  journal={Investigative ophthalmology & visual science},
  year={2003},
  volume={44 7},
  pages={
          3083-93
        }
}
PURPOSE The ability to mount antigen-specific immune reactions in the retina demonstrates local recognition of retinal antigens. However, properties of antigen-presenting cells (APCs) of the retina are uncertain. The current study was undertaken to look for evidence of CD45(+) cells with APC potential in the retina and to examine their in situ and in vitro responses to IFN-gamma and anti-CD40, two stimuli known to upregulate activities associated with antigen presentation. METHODS Mice were… CONTINUE READING
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