CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer.

@article{Saito2013CD44v6EI,
  title={CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer.},
  author={Seiya Saito and Hirohisa Okabe and Masayuki Watanabe and Takatsugu Ishimoto and Masaaki Iwatsuki and Yoshifumi Baba and Youhei Tanaka and Junji Kurashige and Yuji Miyamoto and Hideo Baba},
  journal={Oncology reports},
  year={2013},
  volume={29 4},
  pages={1570-8}
}
CD44 standard isoform (CD44s) is a cancer stem cell marker in many tumors, and is one of the CD44 isoforms.CD44v6 has been reported to correlate with tumor progression and poor prognosis in colorectal cancer. However, the relevance of CD44s and CD44v6 to epithelial-mesenchymal transition (EMT) remains unclear. Immunohistochemistry was performed to investigate the clinical importance of CD44s and CD44v6 and their relevance to EMT in 113… CONTINUE READING
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Biomarkers for epithelial-mesenchymal transitions.

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