CD44s and CD44v6 Expression in Head and Neck Epithelia

  title={CD44s and CD44v6 Expression in Head and Neck Epithelia},
  author={B. Mack and Olivier Gires},
  journal={PLoS ONE},
  pages={1303 - 1313}
BACKGROUND CD44 splice variants are long-known as being associated with cell transformation. Recently, the standard form of CD44 (CD44s) was shown to be part of the signature of cancer stem cells (CSCs) in colon, breast, and in head and neck squamous cell carcinomas (HNSCC). This is somewhat in contradiction to previous reports on the expression of CD44s in HNSCC. The aim of the present study was to clarify the actual pattern of CD44 expression in head and neck epithelia. METHODS Expression… CONTINUE READING


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