CD44 variant isoforms in head and neck squamous cell carcinoma progression.

@article{Wang2009CD44VI,
  title={CD44 variant isoforms in head and neck squamous cell carcinoma progression.},
  author={Steven J. Wang and Gabriel Wong and Anne-Martine R de Heer and Weiliang Xia and Lilly Y. W. Bourguignon},
  journal={The Laryngoscope},
  year={2009},
  volume={119 8},
  pages={
          1518-30
        }
}
OBJECTIVES/HYPOTHESIS The CD44 family of receptors includes multiple variant isoforms, several of which have been linked to malignant properties including migration, invasion, and metastasis. The objective of this study was to investigate the role of the CD44 v3, v6, and v10 variant isoforms in head and neck squamous cell carcinoma (HNSCC) tumor progression behaviors. STUDY DESIGN Laboratory study involving cell cultures and clinical tissue specimens. METHODS Analysis of the expression of… CONTINUE READING
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