CD44 variant exon epitopes in primary breast cancer and length of survival.

@article{Kaufmann1995CD44VE,
  title={CD44 variant exon epitopes in primary breast cancer and length of survival.},
  author={Manfred Kaufmann and Karl Heinz Heider and Hans Peter Sinn and Gunter von Minckwitz and Helmut Ponta and Peter A. Herrlich},
  journal={Lancet},
  year={1995},
  volume={345 8950},
  pages={615-9}
}
CD44 designates a group of closely related cell-surface proteins generated by alternative splicing. We have previously shown that splice variants carrying sequences encoded by exon v6 are preferentially expressed in metastatic animal cancer cell lines and that they confer metastatic behaviour on non-metastatic animal tumour cell lines. In this study we set out to assess the expression of CD44 epitopes specific for variant exon sequences in human breast cancer and their potential for determining… CONTINUE READING

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