CD44-negative cells in head and neck squamous carcinoma also have stem-cell like traits.

Abstract

CD44 is generally accepted as a surrogate marker for head and neck squamous carcinoma cancer stem cells (HNSC CSCs) and only CD44+ HNSC cells have tumour initiating capacity. However, a recent report suggested that CSCs themselves might be heterogenous due to various genetic alterations. Here, we compared in vitro stem-like cell characteristics… (More)
DOI: 10.1016/j.ejca.2012.06.004

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