CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease.

@article{Brennan1999CD44II,
  title={CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease.},
  author={Frank R. Brennan and Janet K O'Neill and Samantha J. Allen and Colin Butter and George Nuki and David Baker},
  journal={Immunology},
  year={1999},
  volume={98 3},
  pages={427-35}
}
Clinical signs of experimental autoimmune encephalomyelitis (EAE) are associated with the selective recruitment of CD4+ memory (CD45RBlow CD44high) T cells into the central nervous system (CNS). However, we have found that many of these recently recruited memory cells are CD44low, suggesting that the CD44 antigen may be involved in, and transiently lost… CONTINUE READING