CD44 in hematological neoplasias

  title={CD44 in hematological neoplasias},
  author={Magdalena Katharina Hertweck and Felix Erdfelder and K S Kreuzer},
  journal={Annals of Hematology},
The CD44 protein family spans a large group of transmembrane glycoproteins acquired by alternative splicing and post-translational modifications. The great heterogeneity in molecular structure is reflected in its various important functions: CD44 mediates (1) interaction between cell and extracellular matrix, (2) signal submission, e.g., by acting as co-receptor for membrane-spanning receptor tyrosine kinases or by association with intracellular molecules initiating several signaling pathways… CONTINUE READING


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