CD44 expression in benign, premalignant, and malignant ovarian neoplasms: relation to tumour development and progression.

@article{Saegusa1999CD44EI,
  title={CD44 expression in benign, premalignant, and malignant ovarian neoplasms: relation to tumour development and progression.},
  author={Makoto Saegusa and Daisuke Machida and Miki Hashimura and Isao Okayasu},
  journal={The Journal of pathology},
  year={1999},
  volume={189 3},
  pages={326-37}
}
To clarify the possible role of CD44 expression in ovarian tumour development and progression, an immunohistochemical investigation was undertaken of a series of 115 carcinomas, 32 tumours with low malignant potential (LMP), and 53 cystadenomas. A combination of the reverse transcription-polymerase chain reaction (RT-PCR) and Southern blot hybridization (SBH) assays was also performed for 17 malignant, four LMP, six cystadenoma, and seven normal ovarian samples. Immunoreactivity scores for… CONTINUE READING

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