CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2.

Abstract

Hyaluronic acid (HA) is a high molecular weight glycosaminoglycan involved in a wide variety of cellular functions. However, its turnover in living cells remains largely unknown. In this study, CD44, a receptor for HA, and hyaluronidase-1, -2, and -3 (Hyal-1, -2 and -3) were stably expressed in HEK 293 cells and the mechanism of HA catabolism was… (More)

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Cite this paper

@article{Harada2007CD44dependentIA, title={CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2.}, author={Hosami Harada and Masaaki Takahashi}, journal={The Journal of biological chemistry}, year={2007}, volume={282 8}, pages={5597-607} }