CD44 Gene Polymorphisms and Environmental Factors on Oral Cancer Susceptibility in Taiwan

@inproceedings{Chou2014CD44GP,
  title={CD44 Gene Polymorphisms and Environmental Factors on Oral Cancer Susceptibility in Taiwan},
  author={Ying-Erh Chou and Ming-Ju Hsieh and Chang Hsin Hsin and Walter Chiang and Yi-Cheng Lai and Yu-Hsien Lee and Shu-Ching Huang and Shun-Fa Yang and Chiao-Wen Lin},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Oral squamous cell carcinoma (OSCC) is the fourth leading cause of male cancer death in Taiwan. Exposure to environmental carcinogens is the primary risk factor for developing OSCC. CD44, a well-known tumor marker, plays a crucial role in tumor cell differentiation, invasion, and metastasis. This study investigated CD44 single-nucleotide polymorphisms (SNPs) with environmental risk factors to determine OSCC susceptibility and clinicopathological characteristics. METHODOLOGY… CONTINUE READING
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