CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

@article{Rosenstein1991CD43AM,
  title={CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1},
  author={Yvonne J. Rosenstein and John K. Park and William C. Hahn and Fred S. Rosen and Barbara E Bierer and Steven J. Burakoff},
  journal={Nature},
  year={1991},
  volume={354},
  pages={233-235}
}
THE protein CD43 (also known as sialophorin, leukosialin, large sialoglycoprotein or gp115) is expressed on the surface of T lymphocytes, monocytes, neutrophils, platelets and some B lymphocytes1–6. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome7, suggesting that CD43 might have a role in T-cell activation. We have shown that expression of human CD43 in an HLA-DR-specific murine T-cell hybridoma enhances the antigen… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 79 CITATIONS

FILTER CITATIONS BY YEAR

1992
2017

CITATION STATISTICS

  • 8 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

Similar Papers

Loading similar papers…