CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus.

@article{Thomsen1998CD40LI,
  title={CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus.},
  author={Allan Randrup Thomsen and Anneline Nansen and Jan Pravsgaard Christensen and Steven Andreasen and Ole Marker},
  journal={Journal of immunology},
  year={1998},
  volume={161 9},
  pages={4583-90}
}
CD40 ligand (CD40L) is an important molecule that is known to be involved in T-B collaboration and certain aspects of cell-mediated immunity. However, its role in antiviral immunity has not been clearly defined as of yet. Therefore, mice with a targeted defect in the gene encoding this molecule were infected with one of two strains of lymphocytic choriomeningitis virus differing markedly in their capacity to spread in the host. Infection with lymphocytic choriomeningitis virus is initially… CONTINUE READING

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