CD40 ligand (CD154) does not contribute to lymphocyte-mediated inhibition of virulent Mycobacterium tuberculosis within human monocytes.

@article{Larkin2002CD40L,
  title={CD40 ligand (CD154) does not contribute to lymphocyte-mediated inhibition of virulent Mycobacterium tuberculosis within human monocytes.},
  author={Rhonda Larkin and Christopher Benjamin and Yen-Ming Hsu and Qing Wen Li and Lynn Zukowski and Richard F. Silver},
  journal={Infection and immunity},
  year={2002},
  volume={70 8},
  pages={
          4716-20
        }
}
Human monocytes displayed increased expression of CD40 following infection with virulent Mycobacterium tuberculosis. Nevertheless, soluble CD40 ligand (CD40L; also designated CD154) had no effect on the intracellular growth of the organism. Restriction of the intracellular growth of M. tuberculosis by peripheral blood lymphocytes and antigen-specific CD4+ T-cell lines likewise was not reduced by blocking anti-CD40L monoclonal antibody 5c8. 

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