CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, leads to a persistent nuclear accumulation of RelB.

Abstract

In this study we analyzed the effect of CD40 stimulation on the activity and nuclear appearance of Rel/nuclear factor kappaB (NF-kappaB) factors in primary murine B lymphocytes. We show that triggering of CD40 signaling pathway(s) by CD40 ligands expressed on L cells led to strong activation of an NF-kappaB-controlled beta-globin reporter gene in primary B… (More)

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@article{Neumann1996CD40BN, title={CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, leads to a persistent nuclear accumulation of RelB.}, author={Meina Neumann and Gerlinde Wohlleben and Sergei Chuvpilo and Barbara Kistler and Thomas Wirth and E. Serfling and Anneliese Schimpl}, journal={Journal of immunology}, year={1996}, volume={157 11}, pages={4862-9} }