CD40-activated B cells as antigen-presenting cells: the final sprint toward clinical application.


Efficient antigen presentation is a prerequisite for the development of a T-cell-mediated immune response in vitro and in vivo. CD40-activated B cells (CD40B cells) are a promising alternative to dendritic cells as professional APCs for immunotherapy. CD40 activation dramatically improves antigen presentation by normal and malignant B cells, efficiently… (More)
DOI: 10.1586/erv.13.39


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