CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater.

@article{Gras2007CD4CC,
  title={CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater.},
  author={Luuk A J Gras and Anouk M Kesselring and James T Griffin and Ard I. van Sighem and Christophe Fraser and Azra C. Ghani and Frank A Miedema and Peter Reiss and Joep M. A. Lange and Frank de Wolf},
  journal={Journal of acquired immune deficiency syndromes},
  year={2007},
  volume={45 2},
  pages={183-92}
}
OBJECTIVE CD4 cell count changes in therapy-naive patients were investigated during 7 years of highly active antiretroviral therapy (HAART) in an observational cohort. METHODS Three endpoints were studied: (1) time to >or=800 CD4 cells/mm in 5299 therapy-naive patients starting HAART, (2) CD4 cell count changes during 7 years of uninterrupted HAART in a subset of 544 patients, and (3) reaching a plateau in CD4 cell restoration after 5 years of HAART in 366 virologically suppressed patients… CONTINUE READING

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