CD4 and CD8 T-lymphocyte recognition of prostate specific antigen in granulomatous prostatitis.

@article{Klyushnenkova2004CD4AC,
  title={CD4 and CD8 T-lymphocyte recognition of prostate specific antigen in granulomatous prostatitis.},
  author={Elena N. Klyushnenkova and Sathibalan Ponniah and Alejandro Rivero Rodriguez and James A Kodak and Dean L. Mann and Alexander J. Langerman and Michael I. Nishimura and Richard Alexander},
  journal={Journal of immunotherapy},
  year={2004},
  volume={27 2},
  pages={136-46}
}
In order to develop immunotherapies for prostate cancer, many groups are exploring vaccination strategies to induce an immune response against prostate specific antigen (PSA). To determine if T-cell recognition of PSA might be a feature of a naturally occurring human disease, we have studied patients with prostatitis, a poorly understood clinical syndrome of men in which there is evidence that an immune response directed against the prostate may be occurring. We wished to determine if a T-cell… CONTINUE READING

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