CD4+ helper T cell depression in autism.

  title={CD4+ helper T cell depression in autism.},
  author={L J Yonk and Reed P. Warren and Rebecca A. Burger and Phyllis Cole and J. Dennis Odell and William L. Warren and Eileen White and Vijendra K. Singh},
  journal={Immunology letters},
  volume={25 4},
CD4+ (helper) T cells are a heterogenous population of lymphocytes including at least two distinct subpopulations. To investigate the possibility that immune abnormalities in some subjects with autism may involve abnormal distributions of CD4+ and/or CD8+ cells, (suppressor) T cells, peripheral blood lymphocytes of 25 autistic subjects were characterized with monoclonal antibodies and flow cytometry. The autistic subjects had a significantly lower percentage and number of CD4+ cells, a lower… CONTINUE READING
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