CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling.

@article{Doherty2009CD4CA,
  title={CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling.},
  author={Taylor A. Doherty and Pejman Soroosh and David H. Broide and Michael Croft},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2009},
  volume={296 2},
  pages={L229-35}
}
The contribution of CD4 T cells and other CD4+ cells to lung inflammation and airway remodeling remains unclear during bouts of chronic exposure to airborne allergen. Previously, murine models have shown that CD4 T cells are required for initiation of acute inflammation and the remodeling process. However, it is unknown whether CD4 T cells or other CD4… CONTINUE READING