CD4+ T lymphocyte subsets express connexin 43 and establish gap junction channel communication with macrophages in vitro.


Gap junction channels constructed of connexins (Cxs) are expressed by peripheral and secondary lymphoid organ-derived lymphocytes. These channels in the plasma membrane play key roles in a range of lymphocyte functions exemplified by the synthesis and secretion of Igs and cytokines and during transmigration across the endothelium. Most recently, their… (More)


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