CD4+ T lymphocyte subsets express connexin 43 and establish gap junction channel communication with macrophages in vitro.

Abstract

Gap junction channels constructed of connexins (Cxs) are expressed by peripheral and secondary lymphoid organ-derived lymphocytes. These channels in the plasma membrane play key roles in a range of lymphocyte functions exemplified by the synthesis and secretion of Igs and cytokines and during transmigration across the endothelium. Most recently, their… (More)

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