CD38 gene polymorphism and risk of chronic lymphocytic leukemia.

  title={CD38 gene polymorphism and risk of chronic lymphocytic leukemia.},
  author={Iryna V Abramenko and Nadiia I Bilous and Gleb V Pleskach and Anatoliy A Chumak and Iryna A Kryachok and Zoya V Martina and Iryna S Dyagil},
  journal={Leukemia research},
  volume={36 10},
rs6449182 CD38 gene polymorphism was determined by polymerase chain reaction with restriction of products in 328 chronic lymphocytic leukemia (CLL) patients and 271 age- and sex-matched controls. An association between GG genotype and CLL risk was found in the whole group of patients (OR=2.12; p=0.009) and in patients with unmutated immunoglobulin heavy chain variable genes (OR=2.17; p=0.011) comparing to the controls. In the subgroup of 174 controls with evaluated lipids the genotype… CONTINUE READING

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