CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.

@article{Hartman2010CD38EF,
  title={CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.},
  author={William R. Hartman and Linda L. Pelleymounter and Irene Moon and Krishna R. Kalari and Mohan Liu and Tse-Yu Wu and Carlos J Escande and Veronica Nin and Eduardo Nunes Chini and Richard M. Weinshilboum},
  journal={Leukemia & lymphoma},
  year={2010},
  volume={51 7},
  pages={1315-25}
}
CD38 is an ecto-enzyme that hydrolyzes NAD. Its expression is a prognostic marker for chronic lymphocytic leukemia. We have characterized individual variation in CD38 expression in lymphoblastoid cell lines from 288 healthy subjects of three ethnicities. Expression varied widely, with significant differences among ethnic groups, and was correlated… CONTINUE READING