CD38/Cyclic ADP-Ribose Regulates Astrocyte Calcium Signaling: Implications for Neuroinflammation and HIV-1-Associated Dementia

@article{Banerjee2008CD38CyclicAR,
  title={CD38/Cyclic ADP-Ribose Regulates Astrocyte Calcium Signaling: Implications for Neuroinflammation and HIV-1-Associated Dementia},
  author={Sugato Banerjee and Timothy F. Walseth and Kathleen Borgmann and Li Wu and Keshore R. Bidasee and Mathur S Kannan and Anuja Ghorpade},
  journal={Journal of Neuroimmune Pharmacology},
  year={2008},
  volume={3},
  pages={154-164}
}
CD38 is a 45-kD ectoenzyme involved in the synthesis of potent calcium (Ca2+)-mobilizing agents, cyclic adenosine diphosphate-ribose (cADPR), and nicotinic acid adenine dinucleotide phosphate (NAADP+). In HIV-1-infected patients, increased CD38 expression on CD8+ T cells is linked to immune system activation and progression of HIV-1 infection. However, the role of CD38 upregulation in astrocyte function and HIV-1-associated dementia (HAD–now called HAND: HIV-1-associated neurocognitive disorder… CONTINUE READING
12 Citations
64 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 64 references

Similar Papers

Loading similar papers…