CD36 is a novel and potential anti-fibrogenic target in albumin-induced renal proximal tubule fibrosis.

@article{Yang2007CD36IA,
  title={CD36 is a novel and potential anti-fibrogenic target in albumin-induced renal proximal tubule fibrosis.},
  author={Yulin Yang and Shyh-Horng Lin and Lea-Yea Chuang and J Y Guh and T B Liao and Tao-chen Lee and Wen-Teng Chang and F. -H. Chang and Min-Yuan Hung and T A Chiang and Chien-Ya Hung Hung},
  journal={Journal of cellular biochemistry},
  year={2007},
  volume={101 3},
  pages={735-44}
}
Albumin is not only a risk factor for diabetic nephropathy (DN), but also a therapeutic target. Hence, scientists have long sought ways to elucidate the interactions between albumin and diabetic renal tubule fibrosis. CD36, a surface receptor for thrombospondin-1, has been reported to interact with latent transforming growth factor-beta1 (TGF-beta1) and activate its fibrogenic bioactivity. This study elucidates the interactions between CD36 and renal tubule fibrosis. LLC-PK1 cells were applied… CONTINUE READING
16 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…