CD36 deficiency protects against malarial anaemia in children by reducing Plasmodium falciparum-infected red blood cell adherence to vascular endothelium.

@article{Chilongola2009CD36DP,
  title={CD36 deficiency protects against malarial anaemia in children by reducing Plasmodium falciparum-infected red blood cell adherence to vascular endothelium.},
  author={Jaffu O Chilongola and Sakurani T Balthazary and Maximillian Mpina and Martin Mhando and Erasto Vitus Mbugi},
  journal={Tropical medicine & international health : TM & IH},
  year={2009},
  volume={14 7},
  pages={810-6}
}
OBJECTIVE CD36 is a receptor that occurs on the surface of activated immune cells, vascular endothelial cells and participates in phagocytosis and lipid metabolism. CD36 is known to be the major endothelial receptor molecule for field isolates of Plasmodium falciparum. A T1264G mutation in exon X of the gene leads to deficiency of CD36. This study aimed at determining associations between CD36 deficiency, P. falciparum in vitro adherence on purified CD36 and anaemia among children in an endemic… CONTINUE READING

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