CD34/CD117 positivity in assessment of prognosis in children with myelodysplastic syndrome.

@article{Tavil2006CD34CD117PI,
  title={CD34/CD117 positivity in assessment of prognosis in children with myelodysplastic syndrome.},
  author={Bet{\"u}l Tavil and M. Huseyin Cetin and Murat Tuncer},
  journal={Leukemia research},
  year={2006},
  volume={30 2},
  pages={222-4}
}
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders that are characterized by morphology identifying dysplastic changes in one or more cell lineages, peripheral blood cytopenias and a propensity to evolve into secondary acute myeloid leukemia (AML). CD34 is commonly expressed in all types of childhood leukemias, whereas CD117 is a reliable and specific marker to detect leukemia cells committed to myeloid lineage. Co-expression of CD34/CD117 may strongly… CONTINUE READING