CD34+ fibrocytes: morphology, histogenesis and function.

@article{Barth2007CD34FM,
  title={CD34+ fibrocytes: morphology, histogenesis and function.},
  author={Peter Barth and Christina Carolin Westhoff},
  journal={Current stem cell research & therapy},
  year={2007},
  volume={2 3},
  pages={
          221-7
        }
}
The connective tissue of virtually all human organs harbors huge amounts of resident CD34(+) fibrocytes. Recent studies have shown that CD34(+) fibrocytes derive from circulating CD14(+) monocytes. CD34(+) fibrocytes are involved in wound healing, act as antigen presenting cells and secrete a multitude of cytokines. Due to their diverse functions CD34(+) fibrocytes play a role in connective tissue diseases, pulmonary fibrosis and tumor associated stromal remodeling. Stromal remodeling… CONTINUE READING

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