CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation.

@article{Oyekunle2006CD34selectedSC,
  title={CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation.},
  author={A A Oyekunle and Ulrike Koehl and Heike Schieder and Francis Ayketang Ayuk and Helmut Renges and Natalja Fehse and Tatjana Zabelina and Boris Fehse and Thomas Klingebiel and Andreas Sputtek and A. R. Zander and Nikolaus Kr{\"o}ger},
  journal={Cytotherapy},
  year={2006},
  volume={8 4},
  pages={375-80}
}
BACKGROUND Poor graft function without rejection may occur after stem cell transplantation (SCT). CD34(+) stem cell boost (SCB) can restore marrow function but may induce or exacerbate GvHD. We therefore investigated the feasibility and efficacy of CD34(+)-selected SCB in some patients with poor graft function. We present the results for eight patients (median age 46 years) transplanted initially for myelofibrosis, acute leukemia, myeloma and NHL. Six patients had received HLA-matched and two… CONTINUE READING

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Fresh or Cryopreserved CD34+-Selected Mobilized Peripheral Blood Stem and Progenitor Cells for the Treatment of Poor Graft Function after Allogeneic Hematopoietic Cell Transplantation.

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CD34(+)-selected stem cell boost without further conditioning for poor graft function after allogeneic stem cell transplantation in patients with hematological malignancies.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2014
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