CD3‐negative, CD20‐positive T‐cell prolymphocytic leukemia: Case report and review of the literature

  title={CD3‐negative, CD20‐positive T‐cell prolymphocytic leukemia: Case report and review of the literature},
  author={K. Tamayose and N. Sato and J. Ando and K. Sugimoto and K. Oshimi},
  journal={American Journal of Hematology},
We report a case of CD3‐negative, CD20‐positive T‐cell prolymphocytic leukemia (T‐PLL). The leukemic cells were of medium‐to‐large size, mature‐looking, and did not have cytoplasmic granules. The leukemic cells were negative for surface CD3, CD2, and CD7 and strongly positive for CD20. T‐cell lineage markers such as CD4, CD5, and cytoplasmic CD3 were also positive. A monoclonal rearrangement of the T‐cell receptor (TCR) β chain gene was detected. CD3‐negative T‐PLL has been reported often, but… Expand
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