CD24 is expressed in gastric parietal cells and regulates apoptosis and the response to Helicobacter felis infection in the murine stomach.

@article{Duckworth2012CD24IE,
  title={CD24 is expressed in gastric parietal cells and regulates apoptosis and the response to Helicobacter felis infection in the murine stomach.},
  author={Carrie A Duckworth and Daniel Clyde and D Mark Pritchard},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2012},
  volume={303 8},
  pages={G915-26}
}
CD24 is expressed in the putative stem cells within several tissues and is overexpressed in gastric and colonic adenocarcinomas. Perturbed CD24 expression may therefore alter the response of gastrointestinal epithelia to damage-inducing stimuli that induce cancer. We have investigated the effects of CD24 deletion on gastric responses to Helicobacter felis infection and γ-irradiation using CD24-null mice. Gastric CD24 expression was determined by immunohistochemistry in C57BL/6 mice. Female CD24… CONTINUE READING
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