CD200Fc reduces LPS-induced IL-1β activation in human cervical cancer cells by modulating TLR4-NF-κB and NLRP3 inflammasome pathway

Abstract

Chronic inflammation plays an important role in tumorigenesis of cervical cancer. CD200Fc, a CD200R1 agonist, has been found to have anti-inflammatory effects in autoimmune diseases and neuro-degeneration. However, the anti-inflammatory effect of CD200Fc on cervical cancer has not yet to be completely understood. This study investigated the anti… (More)
DOI: 10.18632/oncotarget.16596

Topics

6 Figures and Tables

Cite this paper

@inproceedings{He2017CD200FcRL, title={CD200Fc reduces LPS-induced IL-1β activation in human cervical cancer cells by modulating TLR4-NF-κB and NLRP3 inflammasome pathway}, author={Aiqin He and Jia Shao and Yu Zhang and Hong Lu and Zhijun Wu and Yunzhao Xu}, booktitle={Oncotarget}, year={2017} }