CD200 receptor and macrophage function in the intestine.

@article{Bain2012CD200RA,
  title={CD200 receptor and macrophage function in the intestine.},
  author={Calum C Bain and Allan McI Mowat},
  journal={Immunobiology},
  year={2012},
  volume={217 6},
  pages={643-51}
}
CD200 receptor 1 is an inhibitory receptor expressed by myeloid cells which has inhibitory effects on macrophage function after binding its ubiquitously expressed ligand CD200. Recent evidence suggests that this is important in controlling inflammatory reactions in the lung and here we have explored if the CD200R1-CD200 axis plays a similar role in other mucosal surfaces such as the intestine. We show for the first time that CD200R1 is expressed selectively by resident macrophages in normal… CONTINUE READING

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