CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy.

Abstract

CD20 is expressed in approximately one- half of pediatric acute lymphoblastic leukemia (ALL) cases with B-cell precursor (BCP) origin. We observed that it is occasionally up-regulated during treatment. To understand the impact of this on the potential effectiveness of anti-CD20 immunotherapy, we studied 237 CD10(+) pediatric BCP-ALL patients with Berlin… (More)
DOI: 10.1182/blood-2008-06-164129

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@article{Dworzak2008CD20UI, title={CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy.}, author={Michael Dworzak and Angela Schumich and Dieter Printz and Ulrike Poetschger and Zvenyslava Husak and Andishe Attarbaschi and Giuseppe Basso and Giuseppe Gaipa and Richard Ratei and Georg Mann and Helmut Gadner}, journal={Blood}, year={2008}, volume={112 10}, pages={3982-8} }