CD2+ acute promyelocytic leukemia is associated with leukocytosis, variant morphology and poorer prognosis.

@article{Kaito2005CD2AP,
  title={CD2+ acute promyelocytic leukemia is associated with leukocytosis, variant morphology and poorer prognosis.},
  author={Ken Kaito and Takuji Katayama and Hidekazu Masuoka and Kaichi Nishiwaki and Kazumi Sano and Naohiro Sekiguchi and Takeshi Hagino and Masayuki Kobayashi},
  journal={Clinical and laboratory haematology},
  year={2005},
  volume={27 5},
  pages={307-11}
}
The T cell-lineage marker CD2 is sometimes expressed in acute promyelocytic leukemia (APL), and CD2 expression is reported to correlate with some clinical characteristics. However, the significance of CD2 expression in APL has not been fully elucidated. We evaluated CD2 expression in APL treated by the same treatment strategy in a single institute, and whether it had any special characteristics. Among 29 APL, 6 were positive for CD2. Patients with CD2+ APL tended to have a higher leukocyte… CONTINUE READING