CD19/22 balance relates to improvement of disease activity in systemic lupus erythematosus.

@article{Suzuki2006CD1922BR,
  title={CD19/22 balance relates to improvement of disease activity in systemic lupus erythematosus.},
  author={Jun Suzuki and Souichiro Nakano and Yutaka Nakairi and Akiko Mitsuo and Hirofumi Amano and Shinji Morimoto and Yoshiaki Tokano and Yoshinari Takasaki},
  journal={Modern rheumatology},
  year={2006},
  volume={16 4},
  pages={235-8}
}
B cells in patients with systemic lupus erythematosus (SLE) are hyperactivated and B-cell receptor signal transduction may be affected by various response regulators. CD19 and CD22 play a major role as regulators of B-cell response. Therefore, we examined CD19 and CD22 expressions on B cells of patients with SLE, and how they were related to disease activity. Thirty-one patients with active SLE were selected and enrolled in this study. Evaluation of CD19 and CD22 expressions on B cells was… CONTINUE READING

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