CD163: a regulated hemoglobin scavenger receptor with a role in the anti‐inflammatory response

@article{Moestrup2004CD163AR,
  title={CD163: a regulated hemoglobin scavenger receptor with a role in the anti‐inflammatory response},
  author={S{\o}ren Kragh Moestrup and Holger Jon M{\o}ller},
  journal={Annals of Medicine},
  year={2004},
  volume={36},
  pages={347 - 354}
}
CD163 is a hemoglobin scavenger receptor exclusively expressed in the monocyte‐macrophage system. A particularly high expression is seen in macrophages of the ‘alternative activation’ phenotype playing a major role in dampening the inflammatory response and in scavenging components of damaged cells. CD163‐mediated endocytosis of haptoglobin‐hemoglobin complexes formed upon red blood cell hemolysis leads to lysosomal degradation of the ligand protein and metabolism of heme by cytosolic heme… 
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TLDR
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    Scandinavian journal of clinical and laboratory investigation
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Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone
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TLDR
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TLDR
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TLDR
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