CD151 regulates epithelial cell–cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization

@article{Shigeta2003CD151RE,
  title={CD151 regulates epithelial cell–cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization},
  author={Masaki Shigeta and Noriko Sanzen and Masayuki Ozawa and Jianguo G Gu and Hitoshi Hasegawa and Kiyotoshi Sekiguchi},
  journal={The Journal of Cell Biology},
  year={2003},
  volume={163},
  pages={165 - 176}
}
CD151, a member of the tetraspanin family proteins, tightly associates with integrin alpha3beta1 and localizes at basolateral surfaces of epithelial cells. We found that overexpression of CD151 in A431 cells accelerated intercellular adhesion, whereas treatment of cells with anti-CD151 mAb perturbed the integrity of cortical actin filaments and cell polarity. E-Cadherin puncta formation, indicative of filopodia-based adhesion zipper formation, as well as E-cadherin anchorage to detergent… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 62 CITATIONS

FILTER CITATIONS BY YEAR

2004
2018

CITATION STATISTICS

  • 2 Highly Influenced Citations

  • Averaged 3 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

Similar Papers

Loading similar papers…