CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development.

@article{Chen2017CD146CB,
  title={CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development.},
  author={Jianan Chen and Yongting Luo and Hui Hui and Tanxi Cai and Hongxin Huang and Fuquan Yang and Jing Feng and Jingjing Zhang and Xiyun Yan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2017},
  volume={114 36},
  pages={
          E7622-E7631
        }
}
The blood-brain barrier (BBB) establishes a protective interface between the central neuronal system and peripheral blood circulation and is crucial for homeostasis of the CNS. BBB formation starts when the endothelial cells (ECs) invade the CNS and pericytes are recruited to the nascent vessels during embryogenesis. Despite the essential function of pericyte-EC interaction during BBB development, the molecular mechanisms coordinating the pericyte-EC behavior and communication remain… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Claudin-5: gatekeeper of neurological function

  • Fluids and Barriers of the CNS
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 51 REFERENCES