CD14 polymorphisms and serum CD14 levels through childhood: a role for gene methylation?

@article{MuntheKaas2010CD14PA,
  title={CD14 polymorphisms and serum CD14 levels through childhood: a role for gene methylation?},
  author={Monica Cheng Munthe-Kaas and Tale Maehre Torjussen and Kristina Gervin and Karin C L\odrup Carlsen and Kai H{\aa}kon Carlsen and Berit Granum and Hanne Sagsveen Hjorthaug and Dag Erik Undlien and Robert Lyle},
  journal={The Journal of allergy and clinical immunology},
  year={2010},
  volume={125 6},
  pages={1361-8}
}
BACKGROUND CD14 is a pattern-recognition receptor for environmental LPS, and engagement of the CD14-LPS complex activates innate host defense mechanisms. Single nucleotide polymorphisms (SNPs) in the CD14 gene have been associated with soluble CD14 (sCD14) levels, but inconsistencies between studies suggest the presence of regulatory mechanisms hitherto not well understood. OBJECTIVE We sought to investigate possible associations between CD14 SNPs and sCD14 levels at different time points in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…