CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations.

@article{Hold2009CD14159CTAT,
  title={CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations.},
  author={Georgina L Hold and Charles S. Rabkin and Marilie Denise Gammon and Susan H. Berry and Malcolm G. Smith and Jolanta Lissowska and Harvey A. Risch and Wong-Ho Chow and N. Ashley G. Mowat and Thomas L. Vaughan and Emad M. El-Omar},
  journal={European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation},
  year={2009},
  volume={18 2},
  pages={117-9}
}
Host genetic factors play an important role in modifying the risk of human disease, including cancers of the upper gastrointestinal tract, with increasing interest in Toll-like receptor (TLR) signaling and the impact of genetic polymorphisms in these systems. The CD14-159C/T and the TLR9-1237T/C promoter polymorphisms have previously been shown to be associated with various inflammatory conditions including Helicobacter pylori-induced gastritis in Caucasian populations. In this study, we… CONTINUE READING