CD133 induces tumour-initiating properties in HEK293 cells

Abstract

The pentaspan protein CD133 (Prominin-1) is part of the signature of tumour-initiating cells for various cancer entities. The aim of the present study was to investigate the impact of ectopic CD133 expression on tumourigenic properties of otherwise CD133-negative, non-tumourigenic cells in vitro and in vivo. CD133 was stably transfected into human embryonic… (More)
DOI: 10.1007/s13277-012-0568-z

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