CD133 allows elaborated discrimination and quantification of haematopoietic progenitor subsets in human haematopoietic stem cell transplants.

@article{Radtke2015CD133AE,
  title={CD133 allows elaborated discrimination and quantification of haematopoietic progenitor subsets in human haematopoietic stem cell transplants.},
  author={Stefan Radtke and Andr{\'e} G{\"o}rgens and Lambros Kordelas and Markus Schmidt and Klaus R. Kimmig and Angela K{\"o}ninger and Peter A. Horn and Bernd Giebel},
  journal={British journal of haematology},
  year={2015},
  volume={169 6},
  pages={868-78}
}
The success of haematopoietic stem cell (HSC) transplantation largely depends on numbers of transplanted HSCs, which reside in the CD34(+) populations of bone marrow (BM), peripheral blood stem cells (PBSC) and umbilical cord blood (UCB). More specifically HSCs reside in the CD38(low/-) subpopulation, which cannot be objectively discriminated from mature CD34(+)  CD38(+) progenitors. Thus, better marker combinations for the quantification of more primitive haematopoietic stem and progenitor… CONTINUE READING
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