CD133: to be or not to be, is this the real question?

  title={CD133: to be or not to be, is this the real question?},
  author={Elena Irollo and Giuseppe Pirozzi},
  journal={American journal of translational research},
  volume={5 6},
CD133 (promini-1) is a member of the transmembrane glycoprotein family, was initially described as a specific marker to select human hematopoietic progenitor cells. Then, it was recognised as important marker to identify and isolate the specific cell subpopulation termed "cancer stem cells". Many studies showed that CD133(+) cells have stemness properties such as self-renewal, differentiation ability, high proliferation and they are able also to form tumours in xenografts. Moreover it has been… CONTINUE READING

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