CD13 expression is an independent adverse prognostic factor in adults with Philadelphia chromosome negative B cell acute lymphoblastic leukemia.

@article{Craddock2013CD13EI,
  title={CD13 expression is an independent adverse prognostic factor in adults with Philadelphia chromosome negative B cell acute lymphoblastic leukemia.},
  author={Kenneth J. Craddock and Yan Xian Chen and Joseph M Brandwein and Hong Chang},
  journal={Leukemia research},
  year={2013},
  volume={37 7},
  pages={
          759-64
        }
}
In adults with precursor-B lymphoblastic leukemia (BCP-ALL) there remain a majority of patients who fall in an intermediate cytogenetics risk category with a heterogenous outcome. We analyzed immunophenotypic and cytogenetic factors retrospectively in 126 consecutive adults with BCR-ABL negative BCP-ALL who were treated with a pediatric-based protocol at a single institution over a 10 year period. In addition to age, WBC and cytogenetic findings, CD13 positivity was an independent poor… CONTINUE READING
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