CD11c+ CD8+ T Cells Reduce Renal Fibrosis Following Ureteric Obstruction by Inducing Fibroblast Apoptosis

@inproceedings{Wang2016CD11cCT,
  title={CD11c+ CD8+ T Cells Reduce Renal Fibrosis Following Ureteric Obstruction by Inducing Fibroblast Apoptosis},
  author={Haidong Wang and Juan Wang and Yun Bai and Jinwei Li and Lixin Li and Yanjun Dong},
  booktitle={International journal of molecular sciences},
  year={2016}
}
Tubulointerstitial fibrosis is a common consequence of various kidney diseases that lead to end-stage renal failure, and lymphocyte infiltration plays an important role in renal fibrosis. We previously found that depletion of cluster of differentiation 8⁺ (CD8⁺) T cells increases renal fibrosis following ureteric obstruction, and interferon-γ (IFN… CONTINUE READING