CD117 expression in glial tumors

@article{Cetin2005CD117EI,
  title={CD117 expression in glial tumors},
  author={Neslihan Cetin and Gerald A Dienel and Murat Gokden},
  journal={Journal of Neuro-Oncology},
  year={2005},
  volume={75},
  pages={195-202}
}
SummaryC-kit is a proto-oncogene involved in normal growth and development and neoplastic processes, and its product, CD117, is a highly specific immunohistochemical diagnostic marker for gastrointestinal stromal tumors (GISTs). Because GISTs that express immunohistochemically-detectable CD117 respond dramatically to treatment with tyrosine kinase inhibitors, identification of central nervous system tumors that express CD117 might open new therapeutic approaches for treatment of brain tumors… CONTINUE READING

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The study of CD117 expression in glial tumors and its relationship with the tumor-type and grade

  • Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
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